Factors of risk that bear upon the development of diabetic retinopathy
Abstract
Introduction: Diabetic retinopathy is a retinal microangiopathy that provokes anatomical progressive changes in the retina of the patients with diabetes mellitus of long evolution, it is the third worldwide cause of blindness but the first in old fellows productive in developing countries, that it entails an irreversible loss of vision if one does not diagnose and he talks to each other in good timing.
Objective: To describe the behavior of the risk factors in the patients with diabetic retinopathy that attended the retinal consultation of the Hospital Universitario Manuel Ascunce Domenech.
Methods: A descriptive transverse study, in diabetic patients that attended the retinal consultation with the diagnosis of diabetic retinopathy was carried out in the period understood of October from 2020 to February 2021. The population was composed of 115 diabetic patients that attended the consultation, and they fulfilled the criteria of inclusion, they were applied a fill-out form to pick up data. The results related with the following variables: Type of diabetes (type 1, type 2), present-day treatment, glycemic control and risk factors of diabetic retinopathy and severity of the same.
Results: It was more frequent the patients with diabetes type 2, and the proliferative diabetic retinopathy in patients with diabetes type 1. The treatment with hypoglycemic pray to them it was more frequent in frequent users of insulin, the most patients presented glycemic deficient control, the bigger number of patients they had more of 15 years of disease as risk factor, followed of high blood pressure. Only nephropathy did not entail itself as risk factor.
Conclusions: Diabetes type 2 was more frequent than diabetes type 1. The proliferative diabetic retinopathy was frequent in the patients with diabetes type 1. The treatment more used was the oral hypoglycemic ones. Insulin was the treatment used in patients with diabetic retinopathy not proliferative severe and proliferative diabetic retinopathy. The bigger group presented deficient glycemic control. To better glycemic control less severity of her diabetic retinopathies. There was statistical association between diabetic retinopathy and most of the risk factors.
DeCS: DIABETIC RETINOPATHY/therapy; RISK FACTORS; DIABETES MELLITUS; HYPOGLYCEMIC AGENTS/therapeutic use; GLYCEMIC CONTROL.
Downloads
References
1. American Academy of Ophthalmology Retina/Vitreous Panel. Preferred Practice Pattern® Guidelines. Diabetic Retinopathy [Internet]. San Francisco, CA: American Academy of Ophthalmology; 2017 [citado 8 Jun 2021]. Disponible en: https://www.aao.org/Assets/9f2de0c1-1c30-442f-a3bb-c76e2cf19502/636492239481630000/final-diabetic-retinopathy-update-2017-pdf
2. Ministerio de Salud Pública. Anuario Estadístico de Salud 2019 [Internet]. La Habana: Dirección Nacional de Estadísticas; 2020 [citado 8 Jun 2021]. Disponible en: http://files.sld.cu/bvscuba/files/2020/05/Anuario-Electr%C3%B3nico-Espa%C3%B1ol-2019-ed-2020.pdf
3. Rodríguez Rodríguez B, Rodríguez Rodríguez V, López Ramos M, Villares Velázquez Y, Rubio Alemañi E, González Díaz R, et al. Estrategia nacional para la prevención de ceguera por retinopatía diabética. Rev Cubana Oftalmol [Internet]. Ene-Mar 2015 [citado 8 Jun 2021];28(1):[aprox. 10 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21762015000100014
4. Federación Internacional de Diabetes. Atlas de Diabetes de la FID Novena edición [Internet]. Brussels, Belgium: FDI; 2019 [citado 27 May 2021]. Disponible en: https://www.diabetesatlas.org/upload/resources/material/20200302_133352_2406-IDF-ATLAS-SPAN-BOOK.pdf
5. Gasca Cuello D, Martínez Parra JP, Gómez Gordillo JS, Delgado Contreras SL, Fuentes Martínez RA. Manifestaciones de la retinopatía hipertensiva y de la retinopatía diabética en población adulta. Scientific Education Medical Journal [Internet]. 2021 [citado 16 de febrero 2022]; 1(1):[aprox. 8 p.]. Disponible en: http://www.medicalijournal.com.pdf/oft/v1n1
6. Vinces-Chong RI, Villamarin-Vaca ON, Tapia-Mieles AM, Gorozabel-Alarcón JM, Delgado-Gorozabel CJ, Vinces-Zambrano MI. Diabetes Mellitus y su grave afectación en complicaciones típicas. Pol Con [Internet]. 2019 [citado 21 Mar 2021];4(2):[aprox. 18 p.]. Disponible en: https://polodelconocimiento.com/ojs/index.php/es/article/download/901/pdf
7. Murillo García D. Evolución del fondo de ojo con Respecto a las cifras de Hemoglobina Glucada [Internet]. España: Universidad de Extremadura; 2017 [citado 11 Nov 2019]. Disponible en: http://dehesa.unex.es/bitstream/handle/10662/6530/TDUEX_2017_Murillo_Garcia.pdf?sequence=1&isAllowed=y
8. García Ferrer L, Ramos López M, Molina Santana Y, Chang Hernández M, Perera Miniet E, Galindo Reydmond K. Estrategias en el tratamiento de la retinopatía diabética. Rev Cubana Oftalmol [Internet]. Mar 2018 [citado 13 Nov 2021];31(1):[aprox. 10 p.]. Disponible en: http://scielo.sld.cu/pdf/oft/v31n1/a09_614.pdf
9. Nathan DM; DCCT/EDIC Research Group. The diabetes control and complications trial/epidemiology of diabetes interventions and complications study at 30 years: overview. Diabetes Care [Internet]. 2014 [citado 21 Sep 2021];37(1):[aprox. 8 p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867999/pdf/9.pdf.
10. Tobaru Miyashiro L, Guzmán Ahumada M. Retinopatía diabética. Diagnóstico [Internet]. 2019 [citado 11 Abr 2021];58(2):[aprox. 6 p.]. Disponible en: http://142.44.242.51/index.php/diagnostico/article/download/8/8
11. Klein R, Klein BE, Moss SE, Cruickshanks KJ. The Wisconsin Epidemiologic Study of diabetic retinopathy. XXII. the twenty-five-year progression of retinopathy in persons with type 1 diabetes. Arch Ophthalmol [Internet]. 2008 [citado 21 sep 2021];115(11):[aprox. 10 p.]. Disponible en: https://jamanetwork.com/journals/jamaophthalmology/article-abstract/640831
12. American Diabetes Association. 15. Diabetes advocacy: Standards of Medical Care in Diabetesd2018. Diabetes Care [Internet]. 2018 [citado 21 Sep 2021];41(Suppl.1):[aprox. 2 p.]. Disponible en: https://diabetesed.net/wp-content/uploads/2017/12/2018-ADA-Standards-of-Care.pdf
13. Torres Hernández RM, González Jiménez B, Hernández Ojeda H, Gutiérrez Aguilar P, Amaya Herrera LD, Hernández Orozco H. Hiperglucemia persistente asociada a Retinopatía Diabética en Pacientes Diabéticos tipo 2 de la Ciudad de Veracruz. Rev Mex Med Forense [Internet]. 2019 [citado 27 May 2021];4(2):[aprox. 10 p.]. Disponible en: https://www.medigraphic.com/pdfs/forense/mmf-2019/mmf192c.pdf
14. Vallejo Mesa E, Rodríguez Alvira JF. Epidemiología de la retinopatía diabética y su relación con la diabetes. Rev Colomb endocrinol diab metab [Internet]. 2016 [citado 27 Sep 2021];3(1):[aprox. 4 p.]. Disponible en: http://revistaendocrino.org/index.php/rcedm/article/view/19/29
15. Li W, Feng A, Solís Alfonso L, Fernández-Britto Rodríguez JE. Influencia del tabaquismo, la hiper-tensión arterial y la diabetes mellitus en las enfermedades oftalmológicas. Rev Cub Oftalmol [Internet]. 2017 [citado 27 Sep 2021];30(3):[aprox. 14 p.]. Disponible en: http://scielo.sld.cu/pdf/oft/v30n3/oft10317.pdf
16. Adrianzén RE, Rioja M, Manrrique A. Frecuencia y severidad de la retinopatía diabética en pacientes con diabetes mellitus tipo 2 en el Instituto Regional de oftalmología. Rev Peru Med Exp Salud Pública [Internet]. 2019 [citado 17 May 2021];36(2):[aprox. 5 p.]. Disponible en: https://www.scielosp.org/pdf/rpmesp/2019.v36n2/260-264
17. Schreur V, van Asten F, Ng H, Weeda J, Groenewoud JMM, Tack CJ, et al. Risk factors for development and progression of diabetic retinopathy in Dutch patients with type 1 diabetes mellitus. Acta Ophthalmol (Copenh) [Internet]. 2018 [citado 27 Sep 2021];96(5):[aprox. 6 p.]. Disponible en: https://onlinelibrary.wiley.com/doi/epdf/10.1111/aos.13815
18. Pineda Sarabia C, Zarco Vite XJ, Ruiz Morales ML. Retinopatía diabética, una complicación descuidada. Aten Fam [Internet]. 2018 [citado 6 Mar 2021];2582:[aprox. 3 p.]. Disponible en: https://www.medigraphic.com/pdfs/atefam/af-2018/af182i.pdf
19. Oviedo N, Moya E. Retinopatía diabética. Mediciencias uta [Internet]. 2019 [citado 17 May 2021];3(3):[aprox. 15 p.]. Disponible en: https://medicienciasuta.uta.edu.ec/index.php/MedicienciasUTA/article/download/204/137
20. Arellano Barriga GV, Doimeadios Rodríguez Z, Sagué Larrea J. Retinopatía diabética y angiofluoresceinografía. Arch méd Camagüey [Internet]. 2020 [citado 17 May 2021];24(3):[aprox. 13 p.]. Disponible en: http://scielo.sld.cu/pdf/amc/v24n3/1025-0255-amc-24-03-e6812.pdf
21. Hugh Taylor SB. Guías clínicas para el manejo de la patología ocular del diabético [Internet]. Argentina: Consejo Internacional de Oftalmología; 2017 [citado 17 Sep 2021]. Disponible en: http://www.icoph.org/downloads/ICOGuidelinesD iabeticEyeCare2017-Spanish.pdf
22. Cáceres-del-Carpio JH, Cañote Flores R, Montes-Alvis J, Pacheco- Barrios K, Quiroz-Cerna D, Lujan-Donayre VC, et al. Diagnóstico y tratamiento de la retinopatía diabética y edema macular diabético: Guía de práctica clínica del Seguro Social de Salud del Perú (EsSalud). An Fac med [Internet]. 2020 [citado 17 May 2021];81(1):[aprox. 10 p.]. Disponible en: http://www.scielo.org.pe/pdf/afm/v81n1/1025-5583-afm-81-01-00113.pdf
23. Henrique Hirakawa T, do Carmo Costa W, Nakahima F, Costa Ferreira AL, Braga Ribeiro L, Geraldo Ticianeli J, et al. Conocimiento de los pacientes diabéticos que utilizan el Sistema Único de Salud sobre la retinopatía diabética. Rev Bras Oftalmol [Internet]. 2019 [citado 17 Jun 2021];78(2):[aprox. 5 p.]. Disponible en: https://www.scielo.br/pdf/rbof/v78n2/en_0034-7280-rbof-78-02-0107.pdf
24. Núñez-Delgado NG, Vázquez-Zapien LA, Tarré-Álvarez ST, Villegas-Zavala AL, Peña-Ibarra MA, Mora-León F. La retinopatía diabética, una detección oportuna en primer nivel de atención. Re Ocronos [Internet]. 2020 [citado 8 Jun 2021];3(8):129. Disponible en: https://revistamedica.com/retinopatia-diabetica-deteccion/.
25. Yzquierdo Montiel O, Fariñas Falcón Z, Beltrán Fariñas Y, Pérez Marrero FE, Membrides Pérez GD. Caracterización de la retinopatía diabética. Acta Médica del Centro [Internet]. 2019 [citado 16 Sep 2021];13(3):[aprox. 11 p.]. Disponible en: https://www.medigraphic.com/pdfs/medicadelcentro/mec-2019/mec193k.pdf
26. Castillo Otì JM, Cañal Villanueva J, García Urzueta MT, Galván Manso AI, Callejas Herrero MR, Muñoz Cacho P. Prevalencia y factores de riesgo asociados a la retinopatía diabética en Santander. Norte de España. Atenc Prim [Internet]. 2020 [citado 29 Mar 2021];52(1):[aprox. 9 p.]. Disponible en: https://www.elsevier.es/es-revista-atencion-primaria-27-articulo-prevalencia-factores-riesgo-asociados-retinopatia-S0212656718302932
27. Ruiz-Miranda M, Escobar-Yéndez N, Ramos-López M, Hormigo-Puertas I, Duperet-Carvajal D. El impacto social de la retinopatía diabética. Acta Médica [Internet]. 2020 [citado 29 Jun 2021];21(44):e114. Disponible en: http://www.revactamedica.sld.cu/index.php/act/article/view/114/pdf
28. Zhao XY, Xia S, Chen YX. Antivascular endothelial growth factor agents pretreatment before vitrectomy for complicated proliferative diabetic retinopathy: a meta-analysis of randomised controlled trials. Br J Ophthalmol [Internet]. 2018 [citado 29 Jun 2021];102(8):[aprox. 9 p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6059039/pdf/bjophthalmol-2017-311344.pdf
29. Mehta H, Hennings C, Gillies MC, Nguyen V, Campain A, Fraser-Bell S. Anti-vascular endothelial growth factor combined with intravitreal steroids for diabetic macular oedema. Cochrane Database Syst Rev [Internet]. 2018 [citado 29 Jun 2021];4(4):[aprox. 57 p.]. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494419/pdf/CD011599.pdf
30. Mahgoub MM, Macky TA. El efecto de la panfotocoagulación con láser en edema macular diabético con el fotocoagulador Pascal® versus el láser de argón convencional. Ophthalmologica [Internet]. 2017 [citado 6 Mar 2021];238(suppl1):[aprox. 5 p.]. Disponible en: https://www.karger.com/Article/PDF/477512

Published
How to Cite
Issue
Section
License
Copyright: Camagüey Medical Archive Magazine, offers immediately after being indexed in the SciELO Project; Open access to the full text of the articles under the principle of making available and free the research to promote the exchange of global knowledge and contribute to a greater extension, publication, evaluation and extensive use of the articles that can be used without purpose As long as reference is made to the primary source.
Conflicts of interest: authors must declare in a mandatory manner the presence or not of conflicts of interest in relation to the investigation presented.
(Download Statement of potential conflicts of interest)
The Revista Archivo Médico de Camagüey is under a License Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 International (CC BY 4.0).
This license allows others to distribute, to mix, to adjust and to build from its work, even for commercial purposes, as long as it is recognized the authorship of the original creation. This is the most helpful license offered. Recommended for maximum dissemination and use of licensed materials. The full license can be found at: https://creativecommons.org/licenses/