Primary pancreatic leimyoma in a pregnant woman: case report
Abstract
Introduction: Pancreatic tumors during pregnancy are very rare, diagnosis and treatment are always difficult.
Objective: To present the first case of a primary pancreatic leiomyoma in a pregnant woman.
Case report: A 26 years old primiparous pregnant is reported, with no relevant backgrounds. She was in her first trimesters of pregnancy. Diagnosed with a pancreatic tumor during a routine evaluation. She was referred to a multidisciplinary consult, deciding the voluntary interruption of pregnancy, then she is evaluated by the General Surgery specialty clinic for complaining of epigastric pain and hiccup. On physical examination an epigastric tumor was found. Auxiliary exams were normal. Imagenologic studies confirm a tumor in the pancreatic body and tail. Surgical treatment was scheduled, distal pancreatectomy with splenectomy, due to invasion of gastric wall subtotal distal gastrectomy was performed. Patient evolution without complications. Biopsy reported a well capsulated, leiomyoma type, primary mesenchymal pancreatic tumor.
Conclusions: The first case of a primary pancreatic leiomyoma in a pregnant woman is presented. Pancreatic tumors during pregnancy are rare. Multidisciplinary approach is the best way to improve results.
DeCS: LEIOMYOMA; PANCREATIC NEOPLASMS/surgery; PREGNANCY COMPLICATIONS, NEOPLASTIC/diagnosis; NEOPLASMS, CONNECTIVE AND SOFT TISSUE; PANCREATECTOMY.
Downloads
References
1. Reyna Villasmil E. Manejo de neoplasias malignas raras durante el embarazo. Rev perú ginecol obstet [Internet]. 2021 Ene-Mar [citado 09 Nov 2021];67(1). Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S2304-51322021000100007
2. Monteagudo de la Guardia LA, Chamizo Cabrera MG, Martin Pozo Y, Monteagudo Álvarez CJ. Melanoma y embarazo. Medicentro [Internet]. 2020 [citado 09 Nov 2021];24(4). Disponible en: http://medicentro.sld.cu/index.php/medicentro/article/view/3080/2641
3. Revoredo F, de Vinatea J, Reaño G, Villanueva L, Kometter F, Arenas J, et al. Mucinois cystic neoplasms of the pancreas associated with pregnancy. Two case reports. Medicine [Internet]. 2020 Jul [citado 09 Nov 2021];99(31):e21471. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7402798/.
4. Boyd CA, Benarroch-Gampel J, Kilic G, Kruse EJ, Weber SM, Riall TS. Pancreatic Neoplasms in Pregnancy: Diagnosis, Complications and Management. J Gastrointest Surg [Internet]. 2012 May [citado 09 Nov 2021];16(5):1064-71. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3354643/.
5. Iacopi S, Lombardo C, Menonna F, Mazzeo S, Caramella D, Amorese G, et al. Management of pregnancy-associated pancreatic cystic tumors: Review of the literature and results of a Pancreas Club Inc. Survey. Pancreatology [Internet]. 2018 Dic [citado 09 Nov 2021];18(8):905-12. Disponible en: https://pubmed.ncbi.nlm.nih.gov/30274883/.
6. Rodríguez Muñoz MJ, Pinaro Zabala A, Gómez San Román MT. Lipoma pancreático. Apunt Cienc [Internet]. 2017 Ene-Abr [citado 09 Nov 2021];7(1):11-13. Disponible en: http://apuntes.hgucr.es/wp-content/hgucr/pdf/boletin-18.pdf
7. Predescu D. Pancreatic Neuroendocrine Tumor in Pregnancy- Diagnosis and Treatment Management. Chirurgia [Internet]. 2019 Sep [citado 09 Nov 2021];114(5):550. Disponible en: https://www.researchgate.net/publication/336931471_Pancreatic_Neuroendocrine_Tumour_in_Pregnancy_-_Diagnosis_and_Treatment_Management
8. Zhang H, Yu S, Wang W, Cheng Y, Xiao Y, Lu Z, et al. Primary mesenchymal tumors of the pancreas in a single center over 15 years. Oncol Lett [Internet]. 2016 Nov [citado 09 Nov 2021];12(5):4027-34. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104226/.
9. Aragón Mendoza RL, Arenas Gamboa J, Vieira Serna S, Juan Sierra IA. Tumor retroperitoneal primario durante el embarazo: reporte de un caso y revisión de la literatura. Rev Colomb Obstet Ginecol [Internet]. 2020 Abr-Jun [citado 09 Nov 2021];71(2). Disponible en: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0034-74342020000200195
10. Chirag J. ACOG Committee Opinion No. 723. Guidelines for Diagnostic Imaging During Pregnancy and Lactation. Obstet Gynecol [Internet]. 2019 Ene [citado 09 Nov 2021];133(1):186. Disponible en: https://journals.lww.com/greenjournal/Citation/2019/01000/ACOG_Committee_Opinion_No__723__Guidelines_for.28.aspx
11. Folsom SM, Woodruff TK. Good news on the active management of pregnant cancer patients. F1000Res. 2020;9:F1000.
12. Joshi U, Upadhaya SR, Agrawal V, Rana A. Pancreatic Tumors Complicating Pregnancy: A Concern for Fetomaternal Well Being. Int Med Case Rep J [Internet]. 2020 [citado 09 Nov 2021];13:255-59. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367919/.
13. Vujic J, Marsoner K, Lipp-Pump AH, Klaritsch P, Miscinger HJ, Kornprat P. Non-obstetric surgery during pregnancy-an eleven-year retrospective analysis. BMC Pregnancy Childbirth [Internet]. 2019 Oct [citado 09 Nov 2021];19(1):382. Disponible en: https://pubmed.ncbi.nlm.nih.gov/31653246/.
14. Santos D, Calhu A, Bacelar F, Vieira J. Solid pseudopapillary neoplasm of pancreas with distant metastasis during pregnancy: a diagnostic and treatment challenge. BMC Case Rep. 2020;13(12):e237309. doi.org./10.1136/bcr-2020-237209 .
15. Organización Panamericana de la Salud. Clasificación estadística internacional de enfermedades y problemas relacionados con la salud. 10ª revisión [Internet]. Washington, D.C: OPS; 2003 [citado 09 Nov 2021]. Disponible en: https://iris.paho.org/bitstream/handle/10665.2/6282/Volume1.pdf
16. Daghfous A, Rhaiem R, Zehani A, Jouini M, Kacem M, Safta ZB. Laparoscopic treatment of a cephalic pancreatic leiomyoma. Tunis Med [Internet]. 2017 Abr [citado 09 Nov 2021];95(4):310-12. Disponible en: https://pubmed.ncbi.nlm.nih.gov/29492939/.
Published
How to Cite
Issue
Section
License
Copyright: Camagüey Medical Archive Magazine, offers immediately after being indexed in the SciELO Project; Open access to the full text of the articles under the principle of making available and free the research to promote the exchange of global knowledge and contribute to a greater extension, publication, evaluation and extensive use of the articles that can be used without purpose As long as reference is made to the primary source.
Conflicts of interest: authors must declare in a mandatory manner the presence or not of conflicts of interest in relation to the investigation presented.
(Download Statement of potential conflicts of interest)
The Revista Archivo Médico de Camagüey is under a License Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 International (CC BY 4.0).
This license allows others to distribute, to mix, to adjust and to build from its work, even for commercial purposes, as long as it is recognized the authorship of the original creation. This is the most helpful license offered. Recommended for maximum dissemination and use of licensed materials. The full license can be found at: https://creativecommons.org/licenses/









22 julio 2025