Hoffmann syndrome, manifestation of hypothyroidism: presentation of a case

Authors

  • Asmell Ramos-Cabrera HOSPITAL UNIVERSITARIO “MANUEL ASCUNCE DOMENECH” CAMAGÜEY
  • Alexis Culay-Pérez
  • Yamila Rodríguez-Sánchez
  • Alexis Gregori-Caballero

Keywords:

Síndrome de Hoffmann, Hipotiroidismo, Miopatia tiroidea,

Abstract

Background: Hoffmann syndrome is defined as the combination of hypothyroidism with myopathy, rigidity, cramps and muscle hypertrophy. This form of thyroid myopathy is rare and usually accompanies patients with severe and long-evolving hypothyroidism.
Objective: to describe a case with clinic, hormonal and muscle characteristics of a Hoffmann syndrome, as an exceptional manifestation of hyperthyroidism.
Clinical case: 16-year-old, female patient begins to feel muscular discomfort due to pain and fatigue, which gradually increased, the myalgia became intense to the point that did not allow any physical effort, with marked asthenia and later contractions were added painful muscles, motivating her attendance to medical consultation. Associated with these manifestations were very high levels of muscle enzymes. Increased thyroid volume and symptoms and signs suggestive of hypothyroidism are confirmed, which is confirmed after dosages of thyrotropin, thyroxine and triiodothyronine.
Conclusions: the presented case constitutes a characteristic example of the Hoffmann syndrome, which thanks to a detailed and meticulous clinical history showed the presentation of hypothyroidism.

DeCS: HIPOTIROIDISMO /tratamiento farmacológico; HIPOTIROIDISMO/diagnóstico; DEBILIDAD MUSCULAR/diagnóstico; DISTROFIAS MUSCULARES /complicaciones; INFORMES DE CASOS.

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Author Biography

Asmell Ramos-Cabrera, HOSPITAL UNIVERSITARIO “MANUEL ASCUNCE DOMENECH” CAMAGÜEY

MSc. en Urgencias Medicas,  Especialista de Primer Grado en MGI y de Primer y Segundo Grados en Medicina Intensiva y Emergencia. Asistente. Universidad de Ciencias Médicas de Camagüey.  laboro en el Servicio Politrauma Hospital Universitario “Manuel Ascunce Domenech” Camagüey. Cuba.

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Published

2019-03-30

How to Cite

1.
Ramos-Cabrera A, Culay-Pérez A, Rodríguez-Sánchez Y, Gregori-Caballero A. Hoffmann syndrome, manifestation of hypothyroidism: presentation of a case. Arch méd Camagüey [Internet]. 2019 Mar. 30 [cited 2025 Aug. 9];23(2):249-55. Available from: https://revistaamc.sld.cu/index.php/amc/article/view/6049

Issue

Vol. 23 No. 2 (2019)

Section

Case Reports

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