Malignant pleomorphic storiform fibrous histiocytoma of the left arm

Authors

  • Erick Héctor Hernández
  • Gretel Mosquera Betancourt
  • Evarelis Rondón Martínez

Abstract

Background: malignant fibrous histiocytoma is the soft tissue sarcoma most frequent in adulthood. It appears mostly in extremities (70%) and inferior limbs are one of the most affected (60%).
Objective: to present a case of malignant storiform pleomorphic histiocitoma of the left arm who underwent surgical treatment at universitary hospital “Manuel Ascunce Domenech” of Camagüey in 2016.
Clinical case: a 60-year-old-male-patient with a round increasing volume in posterolateral proximal left arm with collateral circulation. A 20 cm diameter smooth was palpated. It was firm, fix and painful mass with negative auscultation. Simple left humerus radiography informed a homogeneous radiopacity in surrounding soft tissues, no periosteal reaction or bone damage. Ecography of soft tissues showed hypoecoic image of 200 x 170 mm between triceps and deltoid muscles reaction, with well-defined pseudocapsule and no bone affection. An aspiration biopsy was conducted resulting in a malignant mesenchimal neoplasia as a possible malignant histiocytoma. Surgical treatment was carried out to remove the tumor with oncologic margins. Final biopsy after immunohystochemical staining revealed a malignant fibrous pleomorphic storiform histiocytoma. The patient was sent to oncologic treatment with radiotherapy and a local recurrence was diagnosed, that is why an amputation was achieved.
Conclusions: malignant fibrous histiocytoma is the most frequent soft tissue sarcoma in adulthood. There are different histological varieties. That is why immunohystochemical staining is a key tool for accurate diagnosis. Surgery and radiotherapy are the best therapeutic combination. Age, tumor depth, histological variety, location, absence of metastasis and size are the most important prognosis factors.
DeCS: HISTIOCYTOMA, MALIGNANT FIBROUS; THERAPEUTICS; SARCOMA/therapy; AGED; CASE REPORTS.

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Published

2017-05-23

How to Cite

1.
Hernández EH, Mosquera Betancourt G, Rondón Martínez E. Malignant pleomorphic storiform fibrous histiocytoma of the left arm. Arch méd Camagüey [Internet]. 2017 May 23 [cited 2025 Sep. 30];21(3):370-7. Available from: https://revistaamc.sld.cu/index.php/amc/article/view/4950

Issue

Vol. 21 No. 3 (2017)

Section

Case Reports

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