Association between Sjögren´s syndrome and tumors: about a case
Keywords:
Linfoma de células B, Linfoma de Células B Grandes Difuso, Linfoma no Hodgkin, Síndrome de Sjögrem, Xerostomía, Xeroftalmia.Abstract
Background: Sjögren´s syndrome is a chronic autoimmune disease. Its causes are multifactorial. It is characterized by infiltration in exocrine glands with mucosae dryness as well as other systemic manifestations. Its evolution and diagnosis are relatively favorable, although sometimes it is associated with developing cancer processes. Consequently, to carry a strict follow-up of these patients is of vital importance.
Objective: to know the association between Sjögren´s syndrome and diffuse large B-cell Non-Hodgkin´s lymphoma.
Clinical case: a forty-five year old female patient, with preceding Sjögren´s syndrome, who attended consultation. She had clinical manifestations that allowed the doctor to make the diagnosis of diffuse large B-cell Non-Hodgkin´s lymphoma.
Conclusions: despite the disease has a favorable development, it can be frequently associated with proliferating lymphoma processes, which risk the patient´s life. It is necessary to search constantly for suspicious signs of tumors in patients with Sjögren´s syndrome, like sudden decrease in rheumatoid factor, the presence of permanent positive antibodies, or appearance of dry syndrome which do not respond to treatment, among others.
DeCS: SJOGREN'S SYNDROME; LYMPHOMA, B-CELL; XEROSTOMIA; MIDDLE AGED; CASE STUDIES.
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