Clinical-epidemiological behavior of oral cáncer in Camagüey

Authors

Abstract

Introduction: Cancer is one of the main causes of morbidity and mortality in the world. In Cuba, it is the second cause of death for all age groups. Oral cancer represents the sixth place among malignant neoplasms with important health and economic effects.
Objective:
To characterize the clinical-epidemiological behavior of oral cancer in Camagüey province.
Methods:
A cross-sectional, descriptive, observational study was designed, the universe consisted of 432 patients diagnosed with malignant tumors in the Head and Neck service of the Maria Curie Provincial Oncology Hospital in Camagüey province in the period from January 2019 to December 2023 and the non-probabilistic convenience sample was made up of 149 patients who presented the primary site of the lesion in the oral cavity.
Results:
The age group of 50-59 years predominated in (39.59 %) n=59 of the patients and (76.51 %) n=114 belonged to the male sex; most of them practiced smoking, which represented (70.46 %) n=105 of the sample studied. The most frequent form of presentation was exophytic form, which was observed in (30.20 %) n=45 of patients; and squamous cell carcinoma constituted the histological diagnosis of (90.60 %) n=135 of malignant lesions. (32.88 %) n=49 of patients had the primary site of oral cancer in the tongue.
Conclusions: The most affected age group was 50-59 years old and the male sex in which oral cancer was most predominant, smoking was present in most patients and pain was the most reported symptom in the first consultation. The most frequent form of presentation was exophytic and squamous cell carcinoma was the most recurrent histological diagnosis. Most patients were diagnosed as stage II.
DeCS: MOUTH/pathology; MOUTH/injuries; ORAL CANCER/diagnosis; SQUAMOUS CELL CARCINOMA/epidemiology; HEAD AND NECK CANCER/pathology.

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Author Biography

Reynier Ramírez-Suarez, Universidad de Ciencias Médicas. Hospital Universitario Manuel Ascunce Domenech. Servicio de Cirugía Maxilofacial. Camagüey, Cuba.

Autor

References

1. Morales Basulto R, Reina Rodríguez YM, Viamontes Beltrán J. Estudio clínico-epidemiológico de pacientes con cáncer en suelo de boca. Medisur [Internet]. 2019 [citado 28 Nov 2023]; 17(5): [aprox. 8 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1727897X2019000500698&lng=es

2. da-Silva-Barros-Cedraz J, Mascarenhas-Nascimento F, dos-Santos-Menezes F, Mitsunari-Takeshita W, Nogueira-dos-Santos N, Trento C, Campos-Oliveira M. Estudio clínico-epidemiológico de pacientes con cáncer bucal en un periodo de trece años. Rev cuba estomatol [Internet]. 2016 [citado 28 Nov 2023]; 53(3): [aprox. 6 p.]. Disponible en: https://revestomatologia.sld.cu/index.php/est/article/view/733

3. Bray F, Parkin DM. African Cancer Registry Network. Cancer in sub-Saharan Africa in 2020: a review of current estimates of the national burden, data gaps, and future needs. Lancet Oncol [Internet]. 2022 [citado 28 Nov 2023]; 23(6): 719-728. Disponible en: https://pubmed.ncbi.nlm.nih.gov/35550275/

4. Dirección de Registros Médicos y Estadísticos de Salud. Anuario estadístico de salud 2022 [Internet]. La Habana: Dirección de Registros Médicos y Estadísticos de Salud; 2022 [citado 28 Nov 2023]. Disponible en: https://dpsalud.ch.gob.cu/2023/10/05/minsap-anuario-estadistico-de-salud-2022/

5. Dhanuthai K, Rojanawatsirivej S, Thosaporn W, Kintarak S, Subarnbhesaj A, Darling M, et al. Oral cancer: A multicenter study. Med Oral Patol Oral Cir Bucal [Internet]. 2018 [cited 2023 Nov 28]; 23(1): e23-e29. Available from: https://pubmed.ncbi.nlm.nih.gov/29274153/

6. Chow LQM. Head and Neck Cancer. N Engl J Med [Internet].2020 [cited 2023 Nov 28]; 382(1): 60-72. Available from: https://pubmed.ncbi.nlm.nih.gov/31893516/

7. González-Moles MÁ, Aguilar-Ruiz M, Ramos-García P. Challenges in the Early Diagnosis of Oral Cancer, Evidence Gaps and Strategies for Improvement: A Scoping Review of Systematic Reviews. Cancers (Basel) [Internet]. 2022 [cited 2023 Nov 28]; 14(19). Available from: https://doi.org/10.3390/cancers14194967

8. González Ruiz I, Ramos García P, Ruiz Ávila I, González Morales MÁ. Early Diagnosis of Oral Cancer: A Complex Polyhedral Problem with a Difficult Solution. Cancers (Basel) [Internet]. 2023 [cited 2023 Nov 28]; 15(13):3270. Available from: https://pubmed.ncbi.nlm.nih.gov/37444379/

9. Bugueño M, Castro S, Cardemil F. Factores de riesgo, etapificación y pronóstico en carcinoma escamoso de cavidad oral. Rev Otorrinolaringol Cir Cabeza Cuello [Internet]. 2022 [citado 8 Ene 2024]; 82(4): [aprox. 5 p.]. Disponible en: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S071848162022000400476&lng=es

10. Walsh T, Macey R, Kerr AR, Lingen MW, Ogden GR, Warnakulasuriya S. Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions. Cochrane Database Syst Rev [Internet]. 2021 [cited 2024 Jan 8]; 7(7): [about 5 screens]. Available from: https://pubmed.ncbi.nlm.nih.gov/34282854/

11. Mateo-Sidrón Antón MC, Somacarrera Pérez ML. Cáncer oral: genética, prevención, diagnóstico y tratamiento. revisión de la literatura. Av Odontoestomatol [Internet]. 2015 [citado 29 Nov 2023]; 31(4): [aprox. 5 p.]. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S021312852015000400002&lng=es

12. Bray F, Laversanne M, Weiderpass E, Soerjomataram I. The ever-increasing importance of cancer as a leading cause of premature death worldwide. Cancer [Internet]. 2021 [cited 2023 Nov 29]; 127(16): [about 7 screens]. Available from: https://pubmed.ncbi.nlm.nih.gov/34086348/

13. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A; et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin [Internet]. 2021 [cited 2023 Nov 29]; 71(3): [about 5 screens]. Available from: https://pubmed.ncbi.nlm.nih.gov/33538338/

14. Asociación Médica Mundial. Declaración de Helsinki de la AMM - Principios éticos para las investigaciones médicas en seres humanos - Principios éticos para las investigaciones médicas en seres humanos [Internet]. España: Asociación Médica Mundial; 2013 [citado 6 Dic 2022]. Disponible en: http://www.redsamid.net/archivos/201606/2013declaracion-helsinki-brasil.pdf?1

15. Peña González A, Arredondo López M, Vila Martínez L. Comportamiento clínico y epidemiológico del cáncer de cavidad oral. Rev cuba estomatol [Internet]. 2006 [citado 7 Ene 2024]; 43(1): [aprox. 5 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S003475072006000100003&lng=es

16. Anis R, Gaballah K. Oral cancer in the UAE: a multicenter, retrospective study. Libyan J Med [Internet]. 2013 [cited 2024 Jan 7]; 8(1): [about 5 p.]. Available from: https://pubmed.ncbi.nlm.nih.gov/23985381/

17. Ghanem AS, Memon HA, Nagy AC. Evolving trends in oral cancer burden in Europe: a systematic review. Front Oncol [Internet]. 2024 [cited 2024 Nov 14];14: 1444326. Available from: https://pubmed.ncbi.nlm.nih.gov/39493458/

18. Franceschi S, Bidoli E, Herrero R, Muñoz N. Comparison of cancers of the oral cavity and pharynx worldwide: etiological clues. Oral Oncol [Internet]. 2000 [citado 2024 Jan 7];36(1):[about 5 p.]. Disponible en: https://pubmed.ncbi.nlm.nih.gov/10889929/

19. Khare M, Dewangan Y, Nayak T, Singh DK, Vibhakar V, Ramesh K. Oral and Esophageal Cancer: Incidence, Prevalence and Correlation in General Indian Population: A retrospective Study. J Pharm Bioallied Sci [Internet] 2021 [cited 2024 Jan 7]; 13(Supl 1): S221-S224. Available from: https://pubmed.ncbi.nlm.nih.gov/34447080/

20. Kruse AL, Bredell M, Grätz KW. Oral cancer in men and women: are there differences? Cirugía Oral Maxilofaca [Internet]. 2011 [cited 2024 Nov 7]; 15(1):51-5. Available from: https://pubmed.ncbi.nlm.nih.gov/21052752/

21. Dhanuthai K, Rojanawatsirivej S, Subarnbhesaj A, Thosaporn W, Kintarak S. A multicenter study of oral malignant tumors from Thailand. J Oral Maxillofac Pathol [Internet]. 2016 [citado 2024 Jan 7]; 20(3): [about 5 screens]. Available from: https://pubmed.ncbi.nlm.nih.gov/27721612/

22. Tsushima F, Sakurai J, Uesugi A. Malignant transformation of oral lichen planus: a retrospective study of 565 Japanese patients. BMC Oral Health [Internet]. 2021 [cited 2024 Jan 7]; 21:298. Available from: https://pubmed.ncbi.nlm.nih.gov/34112142/

23. Álvarez FM, Fortunato LP, Befani Bernal GA, Coto MB, Castellano LNB, Peralta MI. Leucoplasia verrucosa proliferativa: a proposito de un caso. Rev argent dermatol [Internet]. 2019 [citado 8 Ene 2024]; 100(4): [aprox. 8 p.]. Disponible en: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S1851300X2019000400061&lng=es

24. Dhanuthai K, Theungtin N, Theungtin N, Thep-Akrapong P, Kintarak S, Klanrit P, Chamusri N, Sappayatosok K. Pigmented Oral Lesions: A Multicenter Study. Eur J Dent [Internet]. 2022 [cited 2024 Jan 8];16(2): 315-319. Available from: https://pubmed.ncbi.nlm.nih.gov/34753186/

25. Xue J, Yang S, Seng S. Mechanisms of Cancer Induction by Tobacco-Specific NNK and NNN. Cancers (Basel) [Internet]. 2014 [citado 2024 Jan 8]; 6(2): 1138-1156. Available from: https://pubmed.ncbi.nlm.nih.gov/24830349/

26. Cazar Melo DC, Armas Vega AC. Etiología más frecuente del cáncer oral en adultos jóvenes: una revisión de literatura. Revista San Gregorio [Internet]. 2022 [citado 7 Ene 2024]; (52): [aprox. 5 p.]. Disponible en: https://revista.sangregorio.edu.ec/index.php/REVISTASANGREGORIO/article/view/2149

27. Gil Milá JD, Maestre Cabello JR, Martínez Gómez K. Caracterización de pacientes con cáncer oral y su relación con la invasión en profundidad. Rev Finlay [Internet]. 2021 [citado 7 Ene 2024]; 11(4): [aprox. 5 p.]. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S222124342021000400343&lng=es

Published

2024-12-29

How to Cite

1.
Ramírez-Suarez R, Revuelta-Morales CM, Morales-Paz YR, Morales-Basulto RD, Oliva-Espinosa EO-E, Machado-Reyes JA. Clinical-epidemiological behavior of oral cáncer in Camagüey. Arch méd Camagüey [Internet]. 2024 Dec. 29 [cited 2026 Feb. 13];28:e10221. Available from: https://revistaamc.sld.cu/index.php/amc/article/view/10221

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