Regeneración celular en los defectos óseos segmentarios

Authors

  • Yandri Bornot-Duránd Universidad de Ciencias Médicas. Hospital Militar Dr. Fermín Valdés Domínguez. Servicio Ortopedia y Traumatología. Holguín, Cuba. https://orcid.org/0000-0002-8439-9885
  • Gleibis Amparo Ferrer-Matos Universidad de Ciencias Médicas. Hospital Pediátrico Octavio de la Concepción y de la Pedraja. Servicio Terapia Intensiva Pediátrica. Holguín, Cuba. https://orcid.org/0000-0003-1917-5591

Abstract

Introduction: Segmental bone defects are produced by high-energy traumas that cause acute bone loss, occur sub-acutely during surgical debridement of an exposed fracture, and can also be seen in chronic cases such as pseudarthrosis and osteomyelitis, drastically altering the quality of life of the patient.
Objective: To present a patient with a segmental bone defect secondary to hypertrophic nonunion of the right humerus measuring 6.3 cm.
Case report: A 45-year-old male patient, Caucasian, with no personal pathological history, who came to our office referred from another health institution with a diagnosis of hypertrophic pseudoarthrosis of the right humerus of 3 years of evolution. The membrane induction technique (Masquelet) is performed, which was combined with the implantation of autologous adult stem cells in the second surgical time. Bone union was achieved at 12 weeks.
Conclusions: Within the therapeutic variants of the segmental bone defects, the membrane induction technique stands out, which in combination with the use of cell therapy constitutes a promising option, taking into account that a smaller graft volume is needed, rapid consolidation, as well as an economical alternative, and easy to make without great technological complexity.

DeCS: HUMERAL FRACTURES/complications; REGENERATIVE MEDICINE; STEM CELLS; CELL-AND TISSUE-BASED THERAPY; CASE REPORTS.

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References

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Published

2023-11-29

How to Cite

1.
Bornot-Duránd Y, Ferrer-Matos GA. Regeneración celular en los defectos óseos segmentarios. Arch méd Camagüey [Internet]. 2023 Nov. 29 [cited 2025 Dec. 11];27:e9700. Available from: https://revistaamc.sld.cu/index.php/amc/article/view/9700

Issue

Vol. 27 (2023): Publicación continua

Section

Case Reports

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