Behavior of sepsis in the Eduardo Agramonte Piña Provincial Pediatric Hospital
Abstract
Introduction: Currently, sepsis is considered one of the main causes of multiple organ dysfunction and the increase in mortality of patients diagnosed in emergency services. The impact is negative on the health of the population, and the expenses generated in the health system are estimated at several billion dollars.
Objective: To determine the behavior of sepsis in the Eduardo Agramonte Piña Provincial Pediatric Hospital.
Methods: A cross-sectional, retrospective descriptive, observational study was carried out to determine the behavior of sepsis at the Eduardo Agramonte Piña Provincial Pediatric Hospital from January 1st, 2016 to December 31st, 2020. The universe of the study consisted of all the children admitted (1 180) with this diagnosis to the hospital who met the inclusion and exclusion criteria.
Results: A downward trend in sepsis cases was observed from 2016 to 2020. With a predominance of the age group of 1-4 years and male sex. The main diagnosis was acute respiratory infections followed by pneumonia. Most of the patients(90.1 %) were discharged alive.
Conclusions: Recognizing that sepsis is a priority, early admission to intensive care units is necessary to achieve comprehensive management of these patients and thus reduce mortality from this cause.
DeCS: SEPSIS; SHOCK, SEPTIC SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; INTENSIVE CARE UNITS, PEDIATRIC; PNEUMONIA, VIRAL.
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References
1. Baique-Sánchez PM. Sepsis en pediatría: nuevos conceptos. An Fac med [Internet]. 2017 Jul-Set [citado 25 Feb 2020];78(3). Disponible en: http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1025-55832017000300014
2. Hernández García OL, Rodríguez Venegas EC, Ávila Cabreras JA, Vitón Castillo AA, Blanco Rojas AL. Factores pronósticos de mortalidad en pacientes con bacteriemia ingresados en la Unidad de Cuidados Intensivos. Rev cienc méd Pinar Río [Internet]. 2021 [citado 04 May 2021];25(1). Disponible en: http://www.revcmpinar.sld.cu/index.php/publicaciones/article/view/4770/4437
3. Jaramillo-Bustamante JC, Piñeres-Olave BE, González-Dambrauskas S. SIRS o no SIRS: ¿es esa la infección? Una revisión crítica de los criterios de definición de sepsis. Bol Med Hosp Infant Mex [Internet]. 2020 Nov-Dic [citado 14 Jul 2021];77(6). Disponible en: https://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S1665-11462020000600293
4. Reinhart K, Daniels R, Kissoon N, Machado FR, Schachter RD, Finfer S. Recognizing Sepsis as a Global Health Priority-A WHO Resolution. N Engl J Med [Internet]. 2017 Ago [citado 14 Jun 2021];377(5):414-17. Disponible en:
https://pubmed.ncbi.nlm.nih.gov/28658587/
5. Rodríguez Paz Y, Rodríguez Pantoja M, Lemes Sánchez Y, Quesada Castillo Y. Caracterización clínica, epidemiológica y microbiológica de pacientes con sepsis en una unidad de cuidados intensivos. MEDISAN [Internet]. 2020 Mar-Abr [citado 14 Jun 2021];24(2). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30192020000200252
6. Jabornisky R, Sáenz SS, Capocasa P, Jaen R, Moreno RP, Landry L, et al. Epidemiological study of pediatric severe sepsis in Argentina. Arch Argent Pediatr [Internet]. 2019 [citado 16 Sep 2020]; 117(Suppl 3):S135-S156. Disponible en: https://www.sap.org.ar/docs/publicaciones/archivosarg/2019/v117n3a35se.pdf
7. Mignot-Evers L, Raaijmakers V, Buunk G, Brouns S, Romano L, van Herpt T, et al. Comparison of SIRS criteria and qSOFA score for identifying culture-positive sepsis in the emergency department a prospective cross-sectional multicentre study. BMJ Open [Internet]. 2021 Jun [citado 22 Oct 2021];11(6):e041024. Disponible en: https://pubmed.ncbi.nlm.nih.gov/34135028/
8. Harley A, Latour JM, Schlapbach LJ. The Role of Parental Concerns in the Recognition of Sepsis in Children: A Literature Review. Front Pediatr [Internet]. 2019 [citado 14 May 2020];7:161. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6509218/
9. Tan B, Wong JJ, Sultana R, Koh JCJW, Jit M, Mok YH, et al. Global Case-Fatality Rates in Pediatric Severe Sepsis and Septic Shock. JAMA Pediatr [Internet]. 2019 Abr [citado 12 Nov 2020];173(4):352-62. Disponible en: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450287/
10. Cardoso Armas R, Uriarte Méndez AE. Sepsis en edad pediátrica. Rev cuban med int emerg [Internet]. 2021 [citado 20 Jul 2021];20(2). Disponible en: http://www.revmie.sld.cu/index.php/mie/article/view/806
11. Ministerio de Salud Pública. Anuario Estadístico de Salud 2020 [Internet]. La Habana: Dirección de Registros Médicos y Estadísticas de Salud; 2021 [citado 11 Nov 2021]. Disponible en: https://files.sld.cu/bvscuba/files/2021/08/Anuario-Estadistico-Espa%c3%b1ol-2020-Definitivo.pdf
12. González-Ramírez Y, Almaguer-Boch JR. Caracterización clínico epidemiológica de pacientes pediátricos con sepsis atendidos en el municipio Puerto Padre. Rev electrón Dr. Zoilo E Marinello Vidaurreta [Internet]. 2019 [citado 20 Nov 2021];44(5). Disponible en: http://revzoilomarinello.sld.cu/index.php/zmv/article/view/1930/pdf_619
13. Bilbao González K, Carmona Espinosa L, Martell Betancourt NL, Lima Rodríguez M. Terapia con líquidos en niños con choque séptico en una Unidad de Cuidados Intensivos. Acta médica del centro [Internet]. 2017 [citado 23 Nov 2020];11(1). Disponible en: http://www.revactamedicacentro.sld.cu/index.php/amc/article/view/784/957
14. Scott HF, Brou L, Deakyne SJ, Kempe A, Fairclough DL, Bajaj L. Association Between Early Lactate Levels and 30-Day Mortality in Clinically Suspected Sepsis in Children. JAMA Pediatr [Internet]. 2017 Mar [citado 20 May 2019];171(3):249-55. Disponible en: https://pubmed.ncbi.nlm.nih.gov/28068437/
15. Merlán Martínez M, Ferrer Aguilar E, González Morel M. Relación entre el diagnóstico precoz y la mortalidad por sepsis: nuevos conceptos. Medicentro [Internet]. 2021 Abr-Jun [citado 25 Jul 2021];25(2). Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S1029-30432021000200265
16. Piñeres Olave BE, González Dambrauskas S. SIRS o no SIRS: ¿es esa la infección? Una revisión crítica de los criterios de definición de sepsis. Bol Med Hosp Infant Mex [Internet]. 2020 [citado 12 Feb 2021];77(6):[aprox. 9 p.]. Disponible en: https://www.scielo.org.mx/pdf/bmim/v77n6/1665-1146-bmhim-77-6-293.pdf
17. Torres Molina A, Fuentes Lambert JE, Rodríguez Góngora Y, Navarro Caboverde Y, Calzadilla Columbie CC. Aplicación del SOFA score a pacientes con sepsis en Unidad de Cuidados Intensivos Pediátricos. Correo cient méd [Internet]. 2021 [citado 20 Ago 2021];25(2). Disponible en: http://www.revcocmed.sld.cu/index.php/cocmed/article/view/3529/1924
18. Schlapbach LJ, Kissoon N. Defining Pediatric Sepsis. JAMA Pediatr [Internet]. 2018 Abr [citado 04 Ene 2021];172(4):312-314. Disponible en: https://pubmed.ncbi.nlm.nih.gov/29459982/
19. Montero González T, de Mendoza Amat JH, Torres Gómez Y. Dianas de la respuesta inflamatoria sistémica desde nuevas perspectivas. Rev cuban med mil [Internet]. 2019 [citado 04 Ene 2021];48(3). Disponible en: http://www.revmedmilitar.sld.cu/index.php/mil/article/view/296/369
20. Peshimam N, Nadel S. Sepsis in children: state-of-the-art treatment. Ther Adv Infect Dis [Internet]. 2021 Nov [citado 04 Ene 2021];23(8). Disponible en:
https://pubmed.ncbi.nlm.nih.gov/34868580/
21. Cabrita AJ, Pinheiro I, Menezes Falcao L. Rethinking the concept of sepsis and septic shock. Eur J Intern Med [Internet]. 2018 Ago [citado 21 Dic 2020];54(1):1-5. Disponible en: https://pubmed.ncbi.nlm.nih.gov/29921471/

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