Antimicrobial susceptibility of moxifloxacin and amoxicillin clavulanic acid against two periodontopathogens

Authors

  • Carlos Martín Ardila Medina Universidad de Antioquia
  • Nelly Liliana Sánchez Vásquez
  • Carlos Enrique Huapaya Lazo
  • Geovanna Patricia Vallejo Lara

Abstract

Background: a significant increase in the resistance of some antimicrobial periodontopathogens traditionally used as adjuncts in periodontal therapy has been reported.
Objective: to assess the susceptibility of Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis to moxifloxacin and amoxicillin clavulanic acid in patients with chronic periodontitis.
Methods: an observational cross-sectional study of the universe composed of 30 patients with chronic periodontitis was conducted. Microbiological samples processing were performed following protocols described previously. Disk diffusion tests were used to assess the susceptibility of A. actinomycetemcomitans and P. gingivalis against moxifloxacin and amoxicillin clavulanic acid.
Results: p. gingivalis was the most prevalent microorganism in the population studied. The two periodontopathogens grown were highly sensitive to both antimicrobials tested.
Conclusions: A. actinomycetemcomitans and P. gingivalis are highly susceptible to moxifloxacin and amoxicillin clavulanic acid in this population, therefore it is an alternative adjuvant for the treatment of periodontitis.
DeCS: AGGREGATIBACTER ACTINOMYCETEMCOMITANS; CHRONIC PERIODONTITIS; ANTIINFECCIOSOS; AMOXICILLIN-POTASSIUM CLAVULANATE COMBINATION; CROSS-SECTIONAL STUDIES.

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Published

2016-12-08

How to Cite

1.
Ardila Medina CM, Sánchez Vásquez NL, Huapaya Lazo CE, Vallejo Lara GP. Antimicrobial susceptibility of moxifloxacin and amoxicillin clavulanic acid against two periodontopathogens. Arch méd Camagüey [Internet]. 2016 Dec. 8 [cited 2025 Aug. 18];20(6):628-35. Available from: https://revistaamc.sld.cu/index.php/amc/article/view/4789

Issue

Vol. 20 No. 6 (2016)

Section

Original Articles

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