Theoretical approaches: peritumoral tissue histology in patients undergoing surgery for high-grade intracranial tumors
Abstract
Introduction: Intracranial tumors grow and multiply in the brain or its surrounding areas, potentially damaging healthy cells, invading other regions, and causing inflammation, cerebral edema, and increased intracranial pressure.
Objective: To present the theoretical approaches related to the histology of peritumoral tissue in high-grade intracranial tumors.
Methods: A literature review of the state of the art on the topic was conducted to refine a search strategy for source selection. Searches were performed across various databases and platforms: PubMed, LILACS, ClinicalKey, Cumed, Google Scholar, and SciELO Regional. The first 10 screens from each search engine collected a total of 12,235 documents. Publication dates were limited to the study period. From these, 30 documents were selected and classified by type (books, monographs on the Internet, reference works, Web pages, digital magazines, printed magazines); 20 documents from 2019 onwards were found, while updates on the topic were insufficient with only 10 records.
Results: The literature review identified documents on various histological features of peritumoral tissue, including peritumoral edema, inflammatory infiltration, neovascularization, and changes in neuronal histology. In this sense, postoperative complications and the patient's prognosis were identified.
Conclusions: The study highlighted the behavior of the topic, for which no precedents were found in the literature of articles published in Cuba, emphasizing its relevance based on the review. The histological findings of peritumoral tissue and their relationship with postsurgical complications underscore the need for further studies to understand better the nature of these alterations and their impact on prognosis and clinical outcomes.
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