Clinical-epidemiological characterization of adult patients with kidney stones
Abstract
Introduction: Nephron lithiasis is a disease characterized by the presence of crystals in the nephrons, resulting in the formation of kidney stones, tissue damage, and impaired kidney function.
Objective: To describe the clinical and epidemiological characteristics of adult patients with nephron lithiasis.
Methods: A descriptive, cross-sectional study was conducted in the Urology outpatient clinic of the Manuel Ascunce Domenech University Hospital from January 2022 to July 2024. The study population consisted of 145 patients diagnosed with nephron lithiasis, over 19 years of age, and of both sexes. Descriptive statistics and absolute and relative frequency distributions were used. The information was summarized in tables and graphs.
Results: Patients between 30 and 39 years of age predominated, with 47 patients (32.41%), and males, with 96 patients (66.20%). Eighty-five patients (58.62%) had no family history of kidney stones. Lower back pain predominated in 75 patients (51.72%). The predominant laboratory finding was microhematuria in 99 patients (68.28%); calcifications were also prominent in 100 patients (68.97%).
Conclusions: Kidney stones were more common in the third decade of life and in males. More than half of the patients had no family history of kidney stones. Lower back pain was the most common clinical presentation. The most frequent analytical alterations were microhematuria and the type of calcium lithiasis, with a predominance of calcium oxalate.
DeCS: NEPHROLITHIASIS/diagnosis; KIDNEY CALCULI; LOW BACK PAIN; ADULT; UROLITHIASIS.
Downloads
References
1. Medina Escobedo M, Sánchez Pozos K, Gutiérrez Solis AL, Avila Nava A, González Rocha L, Lugo R. Recurrence of Nephrolithiasis and Surgical Events Are Associated with Chronic Kidney Disease in Adult Patients. Medicina (Kaunas) [Internet]. 2022 [citado 15 Feb 2024];58(3):420. Disponible en: https://doi.org/10.3390/medicina58030420
2. Wigner P, Bijak M, Saluk J. Probiotics in the Prevention of the Calcium Oxalate Urolithiasis. Cells [Internet]. 2022 [citado 15 Feb 2024];11(2):284. Disponible en: https://doi.org/10.3390/cells11020284
3. Wagner CA. Etiopathogenic factors of urolithiasis. Arch Esp Urol [Internet]. 2021 [citado 15 Feb 2024];74(1):16–23. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/33459618
4. San Román S, Bruno G, Ottati G, Luna D, Bidegain E; et al. Factores de riesgo litogénicos en obesos mórbidos en el preoperatorio de cirugía bariátrica. Rev Urug Med Interna [Internet]. 2022 [citado 15 Feb 2024];7(1):17–26. Disponible en: https://revistamedicinainterna.uy/index.php/smiu/article/view/169
5. Bacallao Méndez RA, Obregón Rodríguez M, Mañalich Coma R, Gutiérrez García F, Fadragas Fernández AL, Almaguer López M. Caracterización clínico-epidemiológica de la urolitiasis. Rev cuban med [Internet]. 2022 [citado 15 Feb 2024];61(1): e2547. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75232022000100006&Ing=es
6. Ferraro PM, Taylor EN, Curhan GC. Factors associated with sex differences in the risk of kidney stones. Nephrol Dial Transplant [Internet]. 2023 [citado 15 Feb 2024];38(1):177–83. Disponible en: https://academic.oup.com/ndt/article/38/1/177/6524918
7. Wang K, Ge J, Han W, Wang D, Zhao Y, Shen Y; et al. Risk factors for kidney stone disease recurrence: a comprehensive meta-analysis. BMC Urol [Internet]. 2022 [citado 15 Feb 2024];22(1):62. Disponible en: https://doi.org/10.1186/s12894-022-01017-4
8. Galán LLopis JA. Manejo médico de la litiasis urinaria. Arch Esp Urol [Internet]. 2021 [citado 15 Feb 2024];74(1):1–3. Disponible en: https://medicaljournal.com.co/index.php/mj/article/download/85/182
9. Fernández Gallegos AJ, Vásconez Nina JA, Valencia Meléndez JA, Valencia Herrera AR. Metabolismo, diagnóstico y tratamiento de la litiasis renal. Rev Inf Cient [Internet]. 2024 [citado 20 Ene 2024];103(1):1–16. Disponible en: https://revinfcientifica.sld.cu/index.php/ric/article/view/4570
10. Agarwal DK, Krambeck AE, Sharma V, Maldonado FJ, Westerman ME, Knoedler JJ; et al. Treatment of non-obstructive, non-struvite urolithiasis is effective in treatment of recurrent urinary tract infections. World J Urol [Internet]. 2020 [citado 20 Jan 2024];38(8):2029–33. Disponible en: https://doi.org/10.1007/s00345-019-02977- 3
11. Méndez Carvajal AM, Rodríguez López LM, Aranque Alarcón AJ, Hurtado Cerón AN. Aspectos nutricionales en el paciente con prevalencia litiásica, en niños y adultos: Más que una revisión sistemática de la literatura. Scientific & Education Medical Journal [Internet]. 2022 [citado 20 Ene 2024]; 5 (2):47–67. Disponible en: https://medicaljournal.com.co/index.php/mj/article/download/85/182
12. Zisman AL. Effectiveness of Treatment Modalities on Kidney Stone Recurrence. Clin J Am Soc Nephrol [Internet]. 2017 [citado 2024 Jan 20];12(10):1699–708. Disponible en: https://doi.org/10.2215/CJN.11201016
13. Tzelves L, Mourmouris P, Skolarikos A. Comparison of current guidelines on medical management of stone disease. Arch Esp Urol [Internet]. 2021 [citado 15 Feb 2024];74(1):171–82. Disponible en: http://www.ncbi.nlm.nih.gov/pubmed/33459633
14. Peña Moya Y, Cuellar López D, Caron Girón J, Peña Palma S, Castillo Guerra F, Rodríguez Sanabria A; et al. Estudio de la composición química de las litiasis renales y sus factores de riesgo asociados. Medicentro [Internet]. 2024 [citado 15 Feb 2024];28: e4118. Disponible en: https://medicentro.sld.cu/index.php/medicentro/article/view/4118/3322
15. Lorduy Gómez J, Hernández Herazo X, Revollo Baena L. De voz Iriarte C. Factores de riesgo de litiasis renal y su recurrencia en pacientes de Cartagena de Indias. Rev habanera cienc méd [Internet]. 2023 [citado 15 Feb 2024];22(3): e4913. Disponible en: http://www.revhabanera.sld.cu/index.php/rhab/article/%0Aview/4913
16. López Sambrano JY, Jurado Hidalgo ME. Factores de riesgo de la litiasis renal en el Hospital del Instituto Ecuatoriano de Seguridad Social de Manta, 2013. Dom. Cien. [Internet]. 2016 [citado 20 Ene 2024]; 2:132–44. Disponible en: https://dialnet.unirioja.es/ejemplar/481418
17. Nikhade P, Akulwar A, Surpam S, Vikas MS. Clinical profile of patients with renal stone disease in a tertiary care hospital. Int J Health Sci (Qassim) [Internet]. 2022 [citado 20 Jan 2024];6(S3):1–8. Disponible en: https://sciencescholar.us/journal/index.php/ijhs/article/view/5061
18.Kassaw AB, Belete M, Assefa EM, Tareke AA. Prevalence and clinical patterns of urolithiasis in sub-saharan Africa: a systematic review and meta-analysis of observational studies. BMC Nephrol [Internet]. 2024 [citado 20 Jan 2024];25(1):334. Disponible en: https://doi.org/10.1186/s12882-024-03780-y
19. Türk C, Petřík A, Sarica K, Seitz C, Skolarikos A, Straub M; et al. EAU Guidelines on Diagnosis and Conservative Management of Urolithiasis. Eur Urol [Internet]. 2016 [citado 20 Jan 2024];69(3):468–74. Disponible en: https://linkinghub.elsevier.com/retrieve/pii/S0302283815006995
20. Bacallao Méndez RA, Madrid Mancia C, Mañalich Comas R, Gutiérrez García F, Badell Moore A. Trastornos metabólicos renales en pacientes cubanos adultos con litiasis urinarias. Rev Cuba med [Internet]. 2014 [citado 20 Ene 2024];53(4):456–67. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0034-75232014000400009&lng=es.
21. Hernando Domínguez E, Restrepo Valencia CA, Rendón Valencia JF, Aguirre Arango JV. Descripción de características sociodemográficas y clínicas de pacientes con litiasis renal. Rev Colomb Nefrol [Internet]. 2022 Feb [citado 15 Feb 2024];9(1): e554. Disponible en: https://doi.org/10.22265/acnef.9.1.554

Published
How to Cite
Issue
Section
License
Copyright: Camagüey Medical Archive Magazine, offers immediately after being indexed in the SciELO Project; Open access to the full text of the articles under the principle of making available and free the research to promote the exchange of global knowledge and contribute to a greater extension, publication, evaluation and extensive use of the articles that can be used without purpose As long as reference is made to the primary source.
Conflicts of interest: authors must declare in a mandatory manner the presence or not of conflicts of interest in relation to the investigation presented.
(Download Statement of potential conflicts of interest)
The Revista Archivo Médico de Camagüey is under a License Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 International (CC BY 4.0).
This license allows others to distribute, to mix, to adjust and to build from its work, even for commercial purposes, as long as it is recognized the authorship of the original creation. This is the most helpful license offered. Recommended for maximum dissemination and use of licensed materials. The full license can be found at: https://creativecommons.org/licenses/