Modifiable risk factors for Alzheimer’s disease in a medical office population
Abstract
Introduction: In the context of the Cuban population, studies are needed to know early on the factors that can be modified from the first level of care, in a pre-geriatric population at risk of Alzheimer's disease.
Objective: Identify modifiable risk factors for Alzheimer's disease in a pre-geriatric population in a medical office.
Methods: An observational, descriptive, cross-sectional study was carried out from January to December 2023. From a study universe of 118 patients aged 50 to 59 years, a sample of 112 was formed by non-probabilistic sampling and at discretion of the authors. A database was created, and it was processed using descriptive statistics, through mathematical calculations for distribution of absolute and relative frequencies.
Results: The age group of 55-59 years predominated with 52,68 %, and the female sex with 59,82 %, where there was a greater frequency and concurrence of risk factors. Sedentary lifestyle stood out with 58,04 % and social isolation with 39,29 % and low educational level with 35,71 %. Fashion is two risks in general, in both sexes and age groups. Nine out of ten have at least one risk. The low educational level reached 35,71 %, in which sedentary lifestyle and social isolation are more frequent, and in these patients there is a greater number of risk factors per individual.
Conclusions: Sedentary lifestyle, social isolation and low educacional level were identified more frequently. Although the latter is not characteristic of the study sample, it predominated in patients with the greatest number of modifiable risk factors.
DeCS: ALZHEIMER DISEASE/diagnosis; RISK FACTORS; PRIMARY HEALTH CARE; EARLY DIAGNOSIS; DEMENTIA.
Downloads
References
1. WHO [Internet]. Geneva: World Health Organization; 2023 [citado 08 Feb 2024]. Dementia. Disponible en: https://www.who.int/news-room/fact-sheets/detail/dementia
2. Sánchez M, Veja JC. La enfermedad de Alzheimer desde un análisis métrico de la producción científica de Cuba. Rev Cuba Inf Cienc Salud [Internet]. 2016 [citado 08 Feb 2024];27(1):35-55. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S230721132016000100004&lng=es
3. Pérez M, Álvarez T, Martínez EJ, Valdivia S, Borroto I, Pedraza H. El síndrome del cuidador en cuidadores principales de ancianos con demencia Alzhéimer. Gac Méd Espirit [Internet]. 2017 [citado 08 Feb 2024];19(1):38-50. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S160889212017000100007&lng=es
4. Seima MD, Lenardt MH, Caldas CP. Relação no cuidado entre o cuidador familiar e o idoso com Alzheimer. Rev Bras Enferm [Internet]. 2014 [citado 08 Feb 2024];67(2):233-40. Disponible en: https://www.scielo.br/j/reben/a/9yw85WQcHq5RT6RpVmssvxg/abstract/?lang=pt
5. Llibre-Rodríguez JJ, Gutiérrez-Herrera R, Guerra-Hernández MA. Enfermedad de Alzheimer: actualización en su prevención, diagnóstico y tratamiento. Rev haban cienc méd [Internet]. 2022 [citado 08 Feb 2024];21(3):e4702. Disponible en: http://www.revhabanera.sld.cu/index.php/rhab/article/view/4702
6. Esquivel-Tamayo J, Montoya-Pedrón A. Factores de riesgo y biomarcadores de la enfermedad de Alzheimer. Rev cuban med mil [Internet]. 2023 [citado 08 Feb 2024];53(1). Disponible en: https://revmedmilitar.sld.cu/index.php/mil/article/view/16519
7. Livingston G, Huntley J, Sommerlad A, Ames D, Ballard C, Banerjee S, et al. Dementia prevention, intervention, and care: 2020 report of the Lancet Commission. The Lancet [Internet]. 2020 [citado 08 Feb 2024];396(10248):413-446. Disponible en: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30367-6/fulltext
8. Lubben J, Blozik E, Gillmann G, Iliffe S, von Renteln Kruse W, Beck JC, et al. Performance of an abbreviated version of the Lubben Social Network Scale among three European community-dwelling older adult populations. Gerontologist [Internet]. 2006 [citado 08 Feb 2024];46(4):503-13. Disponible en: https://academic.oup.com/gerontologist/article/46/4/503/623897
9. Organización Mundial de la Salud [Internet]. Ginebra: OMS; 2019 [citado 15 Sep 2023]. Demencia. Datos y cifras. Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/dementia/dates
10. Calderón Campos MK, Parodi FJ, Runzer Colmenares MF. Comorbilidades neurológicas y su relación con la velocidad de la marcha en adultos mayores del Centro Médico Naval Cirujano Mayor Santiago Távara 2010-2015. Rev Neuropsiquiatr [Internet]. 2019 [citado 08 Feb 2024];82(2):110-116. Disponible en: https://revistas.upch.edu.pe/index.php/RNP/article/view/3537/3871
11. Lau H, Arimi Fitri LM, Shahar S, Badrasawi M, Clark CB. Factors associated with motoric cognitive risk syndrome among low-income older adults in Malaysia. BMC Public Health [Internet]. 2019 [citado 08 Feb 2024];19(4). Disponible en: https://bmcpublichealth.biomedcentral.com/articles/10.1186/s12889-019-6869-z
12. Ocaña Montoya MC, Montoya Pedrón A, Bolaño Díaz AG. Perfil clínico neuropsicológico del deterioro cognitivo subtipo posible Alzheimer. MEDISAN [Internet]. 2019 [citado 08 Feb 2024];23(5):875-891. Disponible en: http://www.medisan.sld.cu/index.php/san/article/view/2719
13. Hernández Ulloa E, Llibre Rodríguez JJ, Bosh Bayard R, Zayas Llerena T. Prevalencia y factores de riesgo del síndrome demencial en personas mayores. Rev Cubana Med Gen Integr [Internet]. 2021 [citado 08 Feb 2024];37(3):e1409. Disponible en: http://scielo.sld.cu/scielo.php?script=sci_arttext&pid=S0864-21252021000300005&lng=es
14. Mejia-Arango S, Garcia-Cifuentes E, Samper-Ternent R, Borda-MG, Cano-Gutierrez CA. Socioeconomic Disparities and Gender Inequalities in Dementia: a Community-Dwelling Population Study from a Middle-Income Country. Journal of Crosscultural Gerontology [Internet]. 2021 [citado 08 Feb 2024];36(1):105-118. Disponible en: https://link.springer.com/article/10.1007/s10823-020-09418-4
15. Fratiglioni L, Marseglia A, Dekhtyar S. Ageing without dementia: can stimulating psychosocial and lifestyle experiences make a difference? The Lancet Neurology [Internet]. 2020 [citado 08 Feb 2024];19(6):533-543. Disponible en: https://doi.org/10.1016/S1474-4422(20)30039-9
16. Stern Y, Arenaza Urquijo EM, Bartrés Faz D, Belleville S, Cantilon M, Chetelat G, et al. Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance. Alzheimer’s & Dementia: the Journal of the Alzheimer’s Association [Internet]. 2020 [citado 08 Feb 2024];16(9):1305-1311. Disponible en: https://doi.org/10.1016/j.jalz.2018.07.219
17. Nelson ME, Jester DJ, Petkus AJ, Andel R. Cognitive Reserve, Alzheimer's Neuropathology, and Risk of Dementia: A Systematic Review and Meta-Analysis. Neuropsychol Rev [Internet]. 2021 [citado 08 Feb 2024];31(2):233-250. Disponible en: https://link.springer.com/article/10.1007/s11065-021-09478-4
18. Darwish H, Farran N, Assaad S, Chaaya M. Cognitive Reserve Factors in a Developing Country: Education and Occupational Attainment Lower the Risk of Dementia in a Sample of Lebanese Older Adults. Frontiers in Aging Neuroscience [Internet]. 2018 [citado 08 Feb 2024];10:277. Disponible en: https://www.frontiersin.org/articles/10.3389/fnagi.2018.00277/full
19. Sommerlad A, Sabia S, Singh Manoux A, Lewis G, Livingston G. Association of social contact with dementia and cognition: 28-year follow-up of the Whitehall II cohort study. PLOS Medicine [Internet]. 2019 [citado 08 Feb 2024];16(8):e1002862. Disponible en: https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1002862
20. Evans IEM, Martyr A, Collins R, Brayne C, Clare L. Social isolation and cognitive function in later life: a systematic review and metaanalysis. J Alzheimers Dis [Internet]. 2019 [citado 08 Feb 2024];70(s1):S119-S144. Disponible en: https://content.iospress.com/articles/journal-of-alzheimers-disease/jad180501

Published
How to Cite
Issue
Section
License
Copyright: Camagüey Medical Archive Magazine, offers immediately after being indexed in the SciELO Project; Open access to the full text of the articles under the principle of making available and free the research to promote the exchange of global knowledge and contribute to a greater extension, publication, evaluation and extensive use of the articles that can be used without purpose As long as reference is made to the primary source.
Conflicts of interest: authors must declare in a mandatory manner the presence or not of conflicts of interest in relation to the investigation presented.
(Download Statement of potential conflicts of interest)
The Revista Archivo Médico de Camagüey is under a License Creative Commons Attribution-Noncommercial-No Derivative Works 4.0 International (CC BY 4.0).
This license allows others to distribute, to mix, to adjust and to build from its work, even for commercial purposes, as long as it is recognized the authorship of the original creation. This is the most helpful license offered. Recommended for maximum dissemination and use of licensed materials. The full license can be found at: https://creativecommons.org/licenses/